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Old 03-27-2012, 06:19 AM   #1 (permalink)
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One Drug to Shrink All Tumors

A single drug can shrink or cure human breast, ovary, colon, bladder, brain, liver, and prostate tumors that have been transplanted into mice, researchers have found. The treatment, an antibody that blocks a "do not eat" signal normally displayed on tumor cells, coaxes the immune system to destroy the cancer cells.

A decade ago, biologist Irving Weissman of the Stanford University School of Medicine in Palo Alto, California, discovered that leukemia cells produce higher levels of a protein called CD47 than do healthy cells. CD47, he and other scientists found, is also displayed on healthy blood cells; it's a marker that blocks the immune system from destroying them as they circulate. Cancers take advantage of this flag to trick the immune system into ignoring them. In the past few years, Weissman's lab showed that blocking CD47 with an antibody cured some cases of lymphomas and leukemias in mice by stimulating the immune system to recognize the cancer cells as invaders. Now, he and colleagues have shown that the CD47-blocking antibody may have a far wider impact than just blood cancers.
One Drug to Shrink All Tumors - ScienceNOW
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Old 03-27-2012, 06:53 AM   #2 (permalink)
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Old 03-27-2012, 11:49 AM   #3 (permalink)
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Sarah Palin is considered a tumor to many. Can we shrink her too?
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Old 03-27-2012, 12:36 PM   #4 (permalink)
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if the drug had to be inserted rectally, would that be one ring to rule them all?
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Old 04-01-2012, 08:32 AM   #5 (permalink)
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More commentary on the subject at Science Based Medicine. The comments beneath the story are also useful and provide some background context and an idea of how effective this is likely to be.

Science-Based Medicine A Universal Anti-Cancer Drug?
Originally Posted by Ava Glasgow
But I cannot take your arguments seriously when you back them up with links to ridiculously bad information. It's not bad because I disagree with it, it's bad because it really is bad. These sites demonstrate zero knowledge of the science they are discussing, they link almost exclusively to other non-information, and when they DO link to an authoritative source, they misrepresent what the source actually says.
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Old 04-01-2012, 04:46 PM   #6 (permalink)
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All the caution is good and to be expected, but I find this really exciting just as basic research. If nothing else, it's getting an angle on an important part of what some cancers do.
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