In videogames I always play as a female. I usually prefer to play in 3rd person mode - and if I have to stare at ass through 40 hours of gameplay, I prefer it to be female ass.
SL is the exception I guess. Male/Male for me here. I had a female alt, but I only used her to try out a bunch of female stuff and I stopped doing that as the quality and amount of men's stuff has been improving slowly but steadily.